A new class of prescription medications has transformed weight management in recent years. GLP-1 receptor agonists — the same class that includes Ozempic®, Wegovy®, and Zepbound® — are now among the most effective tools available for medically supervised weight loss. Here’s what Canadians need to know.

What Are GLP-1 Medications?

GLP-1 stands for glucagon-like peptide-1, a hormone the body releases after eating. It slows digestion, helps control appetite, and increases insulin release from the pancreas. In people with obesity or diabetes, digestion, appetite control, and insulin release are often impaired. 

GLP-1 medications work by mimicking this natural hormone, helping your brain receive the signal that you’re full — reducing cravings and helping you sustain a caloric deficit more comfortably.

Which Medications Are Approved in Canada?

Four medications are now authorized by Health Canada for long-term weight management: liraglutide (Saxenda®), naltrexone/bupropion (Contrave®), semaglutide (Wegovy®), tirzepatide (Zepbound®). Among these, semaglutide and tirzepatide represent a new generation of GLP-1–based therapies. 

Semaglutide (Wegovy®) is offered at 0.25 mg weekly to start, progressively increased every four weeks until a maintenance dose of 1.7 mg or 2.4 mg is reached, and is approved for use in adults and adolescents above 18 years old. Tirzepatide (Zepbound®), administered at either 2.5, 5, 7.5, 10,12.5, or 15 mg every week, is approved for use in adults in Canada and is a GLP-1/GIP dual agonist. 

How Effective Are These Medications?

On average, people lose up to 20% of their body weight in one year when combined with lifestyle changes. Various clinical research supports these outcomes, and most patients begin noticing appetite changes within the first few weeks.

What About Compounded Versions?

Canada’s updated 2025 pharmacotherapy guidelines recommend against the use of compounded medications or medications other than those approved for weight loss in people with excess adiposity. Our platform only facilitates prescriptions for Health Canada–approved medications issued by licensed Canadian prescribers.

How Can I Access These Medications?

Through our telehealth platform, you can complete a confidential health assessment online. A licensed Canadian prescriber reviews your submission and, if you’re a candidate, issues a prescription that goes directly to a pharmacy. Start your weight loss assessment now.

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