Rybelsus

It is an oral (pill) form of semaglutide that helps reduce appetite and calorie intake, sometimes leading to modest weight loss.

It’s approved for type 2 diabetes, not specifically for weight loss, and should be used under medical supervision.

Rybelsus
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About Rybelsus

1

What Is It?

Rybelsus is the only oral GLP-1 medication currently available in Canada. It contains semaglutide — the same active ingredient as Ozempic and Wegovy — but in tablet form, taken once daily by mouth. It is approved for type 2 diabetes, however, significant weight loss is a well-documented effect, and it is sometimes prescribed off-label for weight management.

2

How Does It Work?

For those who are uncomfortable with injections, oral semaglutide (Rybelsus) is an alternative. It requires daily dosing and must be taken under specific conditions — on an empty stomach, followed by no eating for at least 30 minutes — to allow proper absorption. It works through the same GLP-1 mechanism as Ozempic and Wegovy: reducing appetite, slowing digestion, and promoting fullness.

3

How Is It Taken?

Starting at 3 mg daily for the first 30 days, then increased to 7 mg daily. The dose may be increased to 14 mg daily after 30 days if needed. It must be taken first thing in the morning with no more than 4 oz of water, on an empty stomach, and you must wait at least 30 minutes before eating or drinking anything else.

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